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PubMed é um banco de dados que possibilita a pesquisa bibliográfica em mais de 17 milhões de referências de artigos médicos publicados em cerca de 3.800 revistas científicas .

Página 13 dos resultados de 3665068 itens digitais encontrados em 1.094 segundos

Fluid loading in abdominal surgery - saline versus hydroxyethyl starch (FLASH Trial): study protocol for a randomized controlled trial

Futier, Emmanuel; Biais, Matthieu; Godet, Thomas; Bernard, Lise; Rolhion, Christine; Bourdier, Justine; Morand, Dominique; Pereira, Bruno; Jaber, Samir;
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Text
Publicado em 21/12/2015 Português

Characteristics of leptospirosis with systemic inflammatory response syndrome: a multicenter study

Yilmaz, Hava; Turhan, Vedat; Yasar, Kadriye Kart; Hatipoglu, Mustafa; Sunbul, Mustafa; Leblebicioglu, Hakan
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Text
Publicado em 21/12/2015 Português

Brain mediators of systemic oxidative stress on perceptual impairments in Parkinson’s disease

Lin, Wei-Che; Chou, Kun-Hsien; Lee, Pei-Lin; Huang, Yung-Cheng; Tsai, Nai-Wen; Chen, Hsiu-Ling; Cheng, Kuei-Yueh; Wang, Hung-Chen; Lin, Tsu-Kung; Li, Shau-Hsuan; Chen, Meng-Hsiang; Lu, Cheng-Hsien; Lin, Ching-Po
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Text
Publicado em 21/12/2015 Português

Irrefutable evidence for the use of docetaxel in newly diagnosed metastatic prostate cancer: results from the STAMPEDE and CHAARTED trials

van Soest, Robert J.; de Wit, Ronald
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Text
Publicado em 22/12/2015 Português
Androgen deprivation therapy (ADT) has been used in the treatment of metastatic prostate cancer since the first description of its hormonal dependence in 1941. In 2004, docetaxel chemotherapy became the mainstay of treatment in metastatic castration-resistant prostate cancer (mCRPC), following robust, albeit modest, survival benefit in two randomized phase 3 trials. The recently published CHAARTED trial was the first to show that combining ADT with docetaxel in men with hormone-naïve (hormone-sensitive) metastatic prostate cancer (mHSPC) yielded a remarkable overall survival benefit of 13.6 months as compared with ADT alone. In the current issue of The Lancet, James et al. report results of the STAMPEDE trial in men with high-risk locally advanced or metastatic prostate cancer initiating long-term hormone therapy. The combination of six cycles of docetaxel with ADT in men commencing long-term ADT demonstrated a similar OS benefit compared with standard of care (SOC) by a median of 10 months. Based on the consistency of the data and the firmness of the benefit provided, docetaxel in addition to ADT should be considered SOC for men with newly diagnosed mHSPC.

ATP bioluminescence values are significantly different depending upon material surface properties of the sampling location in hospitals

Shimoda, Tomoko; Yano, Rika; Nakamura, Shinji; Yoshida, Mitsutaka; Matsuo, Junji; Yoshimura, Sadako; Yamaguchi, Hiroyuki
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Text
Publicado em 21/12/2015 Português

Youth injury prevention in Canada: use of the Delphi method to develop recommendations

Pike, Ian; Piedt, Shannon; Davison, Colleen M.; Russell, Kelly; Macpherson, Alison K.; Pickett, William
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Text
Publicado em 22/12/2015 Português

Microarray analysis of Long non-coding RNA expression profiles in human gastric cells and tissues with Helicobacter pylori Infection

Zhu, Hong; Wang, Qiang; Yao, Yizheng; Fang, Jian; Sun, Fengying; Ni, Ying; Shen, Yixin; Wang, Hua; Shao, Shihe
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Text
Publicado em 21/12/2015 Português

The prevalence of axial spondyloarthritis in the UK: a cross-sectional cohort study

Hamilton, Louise; Macgregor, Alex; Toms, Andoni; Warmington, Victoria; Pinch, Edward; Gaffney, Karl
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Text
Publicado em 21/12/2015 Português

A small multigene hydroxyproline-O-galactosyltransferase family functions in arabinogalactan-protein glycosylation, growth and development in Arabidopsis

Basu, Debarati; Tian, Lu; Wang, Wuda; Bobbs, Shauni; Herock, Hayley; Travers, Andrew; Showalter, Allan M.
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Text
Publicado em 21/12/2015 Português

Retroviral DNA—the silent winner: blood transfusion containing latent feline leukemia provirus causes infection and disease in naïve recipient cats

Nesina, Stefanie; Katrin Helfer-Hungerbuehler, A.; Riond, Barbara; Boretti, Felicitas S.; Willi, Barbara; Meli, Marina L.; Grest, Paula; Hofmann-Lehmann, Regina
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Text
Publicado em 21/12/2015 Português

Up-regulation of Orai1 expression and store operated Ca2+ entry following activation of membrane androgen receptors in MCF-7 breast tumor cells

Liu, Guilai; Honisch, Sabina; Liu, Guoxing; Schmidt, Sebastian; Alkahtani, Saad; AlKahtane, Abdullah A.; Stournaras, Christos; Lang, Florian
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Text
Publicado em 21/12/2015 Português

A review and meta-analysis of prospective studies of red and processed meat, meat cooking methods, heme iron, heterocyclic amines and prostate cancer

Bylsma, Lauren C.; Alexander, Dominik D.
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Text
Publicado em 21/12/2015 Português
Prostate cancer remains a significant public health concern among men in the U.S. and worldwide. Epidemiologic studies have generally produced inconclusive results for dietary risk factors for prostate cancer, including consumption of red and processed meats. We aimed to update a previous meta-analysis of prospective cohorts of red and processed meats and prostate cancer with the inclusion of new and updated cohort studies, as well as evaluate meat cooking methods, heme iron, and heterocyclic amine (HCA) intake exposure data. A comprehensive literature search was performed and 26 publications from 19 different cohort studies were included. Random effects models were used to calculate summary relative risk estimates (SRREs) for high vs. low exposure categories. Additionally, meta-regression analyses and stratified intake analyses were conducted to evaluate dose-response relationships. The SRREs for total prostate cancer and total red meat consumption, fresh red meat consumption, and processed meat consumption were 1.02 (95 % CI: 0.92–1.12), 1.06 (95 % CI: 0.97–1.16), and 1.05 (95 % CI: 1.01–1.10), respectively. Analyses were also conducted for the outcomes of non-advanced, advanced, and fatal prostate cancer when sufficient data were available...

Monomethyl fumarate promotes Nrf2-dependent neuroprotection in retinal ischemia-reperfusion

Cho, Hongkwan; Hartsock, Matthew J.; Xu, Zhenhua; He, Meihua; Duh, Elia J.
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Text
Publicado em 21/12/2015 Português

Effective treatment of hypertension by recombinant Lactobacillus plantarum expressing angiotensin converting enzyme inhibitory peptide

Yang, Guilian; Jiang, Yanlong; Yang, Wentao; Du, Fang; Yao, Yunbao; Shi, Chunwei; Wang, Chunfeng
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Text
Publicado em 21/12/2015 Português

Genomic analysis of Luteimonas abyssi XH031T: insights into its adaption to the subseafloor environment of South Pacific Gyre and ecological role in biogeochemical cycle

Zhang, Li; Wang, Xiaolei; Yu, Min; Qiao, Yanlu; Zhang, Xiao-Hua
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Text
Publicado em 21/12/2015 Português

Using network dynamic fMRI for detection of epileptogenic foci

Nedic, Sanja; Stufflebeam, Steven M.; Rondinoni, Carlo; Velasco, Tonicarlo R.; dos Santos, Antonio C.; Leite, Joao P.; Gargaro, Ana C.; Mujica-Parodi, Lilianne R.; Ide, Jaime S.
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Text
Publicado em 21/12/2015 Português

Direct conversion of theophylline to 3-methylxanthine by metabolically engineered E. coli

Algharrawi, Khalid H. R.; Summers, Ryan M.; Gopishetty, Sridhar; Subramanian, Mani
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Text
Publicado em 21/12/2015 Português

Monitoring bone and soft-tissue tumors after carbon-ion radiotherapy using 18F-FDG positron emission tomography: a retrospective cohort study

Yanagawa, Takashi; Saito, Kenichi; Kiyohara, Hiroki; Ohno, Tatsuya; Nakano, Takashi; Takagishi, Kenji
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Text
Publicado em 21/12/2015 Português

Deficiency of myotubularin-related protein 14 influences body weight, metabolism, and inflammation in an age-dependent manner

Lv, Yin; Xue, Lu; Cai, Congli; Liu, Qing-Hua; Shen, Jinhua
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Text
Publicado em 21/12/2015 Português

A nutrition and conditioning intervention for natural bodybuilding contest preparation: observations and suggestions

Gentil, Paulo
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Text
Publicado em 21/12/2015 Português
Bodybuilding is full of myths and practices that are contrary to the scientific literature, which can lead to health problems. Adopting a scientifically designed approach is very important, as it may help bodybuilders to achieve better results while preserving their health. However, I have some criticism regarding some practices adopted in the referred article as ad libitum ingestion of sugar-free cordial and flavored tea and the performance of the exercise in fasted state, as it seems to bring no benefit and have some potential problems. Some suggestion are made in order to preserve FFM, like changing training split and exercise selection; increasing carbohydrate ingestion and decreasing protein intake; changing the resistance training stimuli and reducing the volume of aerobic exercises and increase its intensity.