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Perfil cognitivo em idosas de dois serviços públicos em São Luís - MA; Socio-demographic factors affecting cognitive performance in older women

CORREIA, Marcius Vinícius Gonçalves; TEIXEIRA, Claudia Cristina Gomes; ARAÚJO, John Fontenele; BRITO, Luciane Maria Oliveira; FIGUEIREDO NETO, José Albuquerque de; CHEIN, Maria Bethânia da Costa; COIMBRA, Liberata Campos; MESQUITA, Emygdia Rosa do Re
Fonte: Faculdade de Medicina da Universidade de São Paulo Publicador: Faculdade de Medicina da Universidade de São Paulo
Tipo: Artigo de Revista Científica
Português
Relevância na Pesquisa
26.54%
CONTEXTO: Este estudo procurou estabelecer, sob o ponto de vista descritivo, o nível de cognição e variáveis sociodemográficas associadas em mulheres da sétima à nona década, em dois serviços públicos, na cidade de São Luís (MA). OBJETIVOS: Estudar o nível de cognição pelo Miniexame do Estado Mental (MMSE) e variáveis sociodemográficas associadas em mulheres da sétima à nona década, em dois serviços públicos, na cidade de São Luís (MA). MÉTODOS: Durante quatro meses um questionário com as variáveis sociodemográficas e o Miniexame do Estado Mental (MMSE) foram aplicados em pacientes ambulatoriais. As voluntárias foram avaliadas nos ambulatórios de Neurologia do Hospital Universitário Presidente Dutra e do Hospital Estadual Carlos Macieira. RESULTADOS: Oitenta pacientes foram avaliadas - 31,2% foram classificadas com transtorno cognitivo ao MEEM; 71,4% destas tinham entre 81 e 85 anos. Transtorno cognitivo estava presente em 65% das pacientes com nível educacional inferior a sete anos. Em relação ao nível de renda e cognição, foi observado que 30,4% das pacientes que apresentavam nível de renda menor que um a dois salários mínimos eram classificadas com transtorno cognitivo. Das 33 voluntárias que tinham cuidador direto...

Validação da versão em português da entrevista telefônica para avaliação do estado cognitivo - modificada (TICS-M) em pacientes acometidos por acidente vascular cerebral; Validation of the portuguese version of the telephone interview for cognitive status - modified (tics-m) among post-stroke patients

Baccaro, Alessandra Fernandes
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 04/06/2014 Português
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Introdução: O AVC (acidente vascular cerebral) é uma das mais importantes causas de alterações neuropsicológicas. Uma avaliação cognitiva inicial realizada por telefone implicaria em um diagnóstico mais precoce de prejuízo cognitivo e demência, reduzindo custos e tempo. Objetivo: Examinar as propriedades psicométricas da versão brasileira da Entrevista Telefônica para Avaliação do Estado Cognitivo - Modificada (TICS-M) em pacientes pós-AVC. Métodos: Previamente à validação da TICS-M em indivíduos acometidos por AVC, foi realizada tradução para o Português do Brasil e adaptação transcultural da versão original da TICS-M em uma amostra de 30 sujeitos não clínicos. Após esta fase, um subgrupo de 61 pacientes com AVC, participantes do Estudo da Mortalidade e Morbidade do AVC (EMMA) que ocorre no Hospital Universitário da Universidade de São Paulo, foram convidados a participar da validação da TICS-M, seis meses após o evento agudo. A TICS-M foi aplicada em três momentos: avaliação inicial (entrevista presencial), uma e duas semanas após a primeira avaliação. Na avaliação inicial, além da TICS-M, questionários adicionais foram aplicados para avaliar a cognição: MoCA (Montreal Cognitive Assessment)...

Análise configuracional da forma urbana e sua estrutura cognitiva

Faria, Ana Paula Neto de
Fonte: Universidade Federal do Rio Grande do Sul Publicador: Universidade Federal do Rio Grande do Sul
Tipo: Tese de Doutorado Formato: application/pdf
Português
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O presente trabalho investiga as características configuracionais que o sistema urbano adquire ao ser mentalmente organizado pelos indivíduos. A estrutura de conhecimento amplamente compartilhada, definida na literatura como "imagem pública", é abordada enquanto parte integrante e indissociável do sistema urbano. A temática é tratada dentro de uma abordagem sistêmica, com o auxílio de modelagem computacional e métodos de análise de redes. Os modelos de simulação foram capazes de replicar muitos dos entendimentos constantes dos trabalhos da área cognitiva, validado, deste modo, a metodologia empregada. A análise das características configuracionais do sistema urbano, composto por seus espaços físicos penetráveis e as informações cognitivamente estruturadas, apontou diversas propriedades estruturais como importantes para o entendimento do funcionamento da cognição ambiental e do papel desempenhado pelos diversos tipos de informações ambientais. Muitos dos resultados obtidos se mostraram comuns entre as cidades analisadas, sugerindo a universalidade de algumas características configuracionais e uma possível influência de aspectos funcionais da cognição ambiental. Foi possível também descrever o papel desempenhado pela configuração morfológica do espaço urbano nas características qualitativas do sistema urbano cognitivamente estruturado.; This study investigates the configuracional properties acquired by urban systems when mentally organized by individuals. The widely shared knowledge structures...

Abordagens bio-inspiradas aplicadas ao estudo da cognição: um encontro entre biologia, psicologia e filosofia

Junqueira, Luís Henrique Féres
Fonte: Universidade Estadual Paulista (UNESP) Publicador: Universidade Estadual Paulista (UNESP)
Tipo: Dissertação de Mestrado Formato: 105 f.
Português
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Pós-graduação em Filosofia - FFC; É antiga a preocupação do ser humano com as questões relacionadas ao conhecimento, incluindo as discussões sobre a sua origem, seu aprendizado, sobre a nossa capacidade de utiliza-lo e sobre as características específicas da cognição humana. Essa preocupação remonta aos antigos filósofos gregos (2.500 A.C.), desenvolvendo-se posteriormente a partir da abordagem da Epistemologia, originária da Filosofia ocidental, e mais recentemente a partir do Funcionalismo, pertencente aos estudos em Filosofia da Mente e em Ciência Cognitiva. Essa última abordagem, em particular, contribuiu para o surgimento de programas de pesquisas que procuram entender o funcionamento da mente humana com a ajuda do computador. A Ciência Cognitiva possui fortes ligações com as pesquisas em Inteligência Artificial, e ambas vem se desenvolvendo desde a década de 1950. Mais recentemente, a partir da década de 1980, uma nova área de estudos surgiu, formada por pesquisas em Vida Artificial, que trabalha com a possibilidade de síntese de entidades vivas, por meios artificiais, e desde então vem chamando a atenção de pesquisadores interessados no estudo da cognição. Enquanto a Ciência Cognitiva tem ligações estreitas com a Filosofia e a Psicologia...

Genetic effects on human cognition: lessons from the study of mental retardation syndromes

Nokelainen, P; Flint, J
Fonte: BMJ Group Publicador: BMJ Group
Tipo: Artigo de Revista Científica
Publicado em /03/2002 Português
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26.54%
The molecular basis of human cognition is still poorly understood, but recent advances in finding genetic mutations that result in cognitive impairment may provide insights into the neurobiology of cognitive function. Here we review the progress that has been made so far and assess what has been learnt from this work on the relation between genes and cognitive processes. We review evidence that the pathway from genetic lesion to cognitive impairment can be dissected, that some genetic effects on cognition are relatively direct and we argue that the study of mental retardation syndromes is giving us new clues about the biological bases of cognition.

Cognitive cladistics and cultural override in Hominid spatial cognition

Haun, Daniel B. M.; Rapold, Christian J.; Call, Josep; Janzen, Gabriele; Levinson, Stephen C.
Fonte: National Academy of Sciences Publicador: National Academy of Sciences
Tipo: Artigo de Revista Científica
Português
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26.54%
Current approaches to human cognition often take a strong nativist stance based on Western adult performance, backed up where possible by neonate and infant research and almost never by comparative research across the Hominidae. Recent research suggests considerable cross-cultural differences in cognitive strategies, including relational thinking, a domain where infant research is impossible because of lack of cognitive maturation. Here, we apply the same paradigm across children and adults of different cultures and across all nonhuman great ape genera. We find that both child and adult spatial cognition systematically varies with language and culture but that, nevertheless, there is a clear inherited bias for one spatial strategy in the great apes. It is reasonable to conclude, we argue, that language and culture mask the native tendencies in our species. This cladistic approach suggests that the correct perspective on human cognition is neither nativist uniformitarian nor “blank slate” but recognizes the powerful impact that language and culture can have on our shared primate cognitive biases.

Office management of elderly hypertensive patients. Focusing on cognition and function.

Rockwood, K.; Freter, S. H.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /12/2001 Português
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OBJECTIVE: To review office management of elderly hypertensive patients and to focus on cognition and function both as ways to stratify who gets treated and as end points for treatment. QUALITY OF EVIDENCE: Relevant papers were identified through a MEDLINE search from January 1994 to March 2000, using the MeSH terms hypertension, aged, aged 80 and over, cognition, activities of daily living, therapeutics, hypotension orthostatic, and dementia. Many well conducted randomized controlled trials were found and are included. MAIN MESSAGE: Treatment of combined and systolic hypertension up to age 80 is clearly worthwhile; beyond age 85, other factors (chiefly cognitive and functional impairment) mitigate most routine recommendations. Successful treatment is individualized, taking into account comorbid conditions and their effect on cognition and function. Age is useful for thinking about groups, not individuals: as people age, risk of cognitive and functional impairment increases, but even very elderly people (> 85 years) with no impairment should be treated as younger patients are. Elderly people with signs of having a "brain at risk" should be managed with special vigilance. CONCLUSION: Good evidence supports treating elderly people, who are otherwise well and are cognitively and functionally intact...

Dysregulation of X-Linked Gene Expression in Klinefelter’s Syndrome and Association With Verbal Cognition

Vawter, Marquis P.; Harvey, Philip D.; DeLisi, Lynn E.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em 05/09/2007 Português
Relevância na Pesquisa
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Klinefelter’s Syndrome (KS) is a chromosomal karyotype with one or more extra X chromosomes. KS individuals often show language impairment and the phenotype might be due to overexpression of genes on the extra X chromosome(s). We profiled mRNA derived from lymphoblastoid cell lines from males with documented KS and control males using the Affymetrix U133P microarray platform. There were 129 differentially expressed genes (DEGs) in KS group compared with controls after Benjamini–Hochberg false discovery adjustment. The DEGs included 14 X chromosome genes which were significantly over-represented. The Y chromosome had zero DEGs. In exploratory analysis of gene expression–cognition relationships, 12 DEGs showed significant correlation of expression with measures of verbal cognition in KS. Overexpression of one pseudoautosomal gene, GTPBP6 (GTP binding protein 6, putative) was inversely correlated with verbal IQ (r = −0.86, P < 0.001) and four other measures of verbal ability. Overexpression of XIST was found in KS compared to XY controls suggesting that silencing of many genes on the X chromosome might occur in KS similar to XX females. The microarray findings for eight DEGs were validated by quantitative PCR. The 14 X chromosome DEGs were not differentially expressed in prior studies comparing female and male brains suggesting a dysregulation profile unique to KS. Examination of X-linked DEGs...

Overlapping Numerical Cognition Impairments In Children With Chromosome 22q11.2 Deletion Or Turner Syndromes

Simon, T.J.; Takarae, Y.; DeBoer, T.; McDonald-McGinn; Zackai, E.H.; Ross, J.L.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Português
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26.54%
Children with one of two genetic disorders (chromosome 22q11.2 deletion syndrome and Turner syndrome) as well typically developing controls, participated in three cognitive processing experiments. Two experiments were designed to test cognitive processes involved in basic aspects numerical cognition. The third was a test of simple manual motor reaction time. Despite significant differences in global intellectual abilities, as measured by IQ tests, performance on the two numerical cognition tasks differed little between the two groups of children with genetic disorders. However, both performed significantly more poorly than did controls. The pattern of results are consistent with the hypothesis that impairments were not due to global intellectual ability but arose in specific cognitive functions required by different conditions within the tasks. The fact that no group differences were found in the reaction time task, despite significant differences in the standardized processing speed measure, further supports the interpretation that specific cognitive processing impairments and not global intellectual or processing speed impairments explain the pattern of results. The similarity in performance on these tasks of children with unrelated genetic disorders counters the view that numerical cognition is under any direct genetic control. Instead...

Before and below ‘theory of mind’: embodied simulation and the neural correlates of social cognition

Gallese, Vittorio
Fonte: The Royal Society Publicador: The Royal Society
Tipo: Artigo de Revista Científica
Português
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26.54%
The automatic translation of folk psychology into newly formed brain modules specifically dedicated to mind-reading and other social cognitive abilities should be carefully scrutinized. Searching for the brain location of intentions, beliefs and desires—as such—might not be the best epistemic strategy to disclose what social cognition really is. The results of neurocognitive research suggest that in the brain of primates, mirror neurons, and more generally the premotor system, play a major role in several aspects of social cognition, from action and intention understanding to language processing. This evidence is presented and discussed within the theoretical frame of an embodied simulation account of social cognition. Embodied simulation and the mirror neuron system underpinning it provide the means to share communicative intentions, meaning and reference, thus granting the parity requirements of social communication.

Cognitive Neuroscience-Based Approaches to Measuring and Improving Treatment Effects on Cognition in Schizophrenia: The CNTRICS Initiative

Carter, Cameron S.; Barch, Deanna M.
Fonte: Oxford University Press Publicador: Oxford University Press
Tipo: Artigo de Revista Científica
Português
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26.54%
The goal of this article is to discuss ways to further improve the search for potentially procognitive agents that could be used to enhance cognition and functional outcome in schizophrenia. In particular, we focus on the potential advantages to this process of using a contemporary, cognitive neuroscience-based approach to measuring cognitive function in clinical trials of procognitive agents in schizophrenia. These tools include computer-administered tasks that measure specific cognitive systems (such as attention, working memory, long-term memory, cognitive control) as well as the component cognitive processes that comprise these more overarching systems. The advantages of using these tools include the ability to identify and use homologous animal and human models in the drug discovery and testing process and the ability to incorporate noninvasive functional imaging measures into clinical trial contexts at several different phases of the drug development process. However, despite the clear potential advantages to using such methods, a number of barriers exist to their translation from basic science tools to tools for drug discovery. We discuss the development and implementation of a new project, Cognitive Neuroscience Treatment to Improve Cognition in Schizophrenia...

Impaired cognition and attention in adults: pharmacological management strategies

Allain, Hervé; Akwa, Yvette; Lacomblez, Lucette; Lieury, Alain; Bentué-Ferrer, Danièle
Fonte: Dove Medical Press Publicador: Dove Medical Press
Tipo: Artigo de Revista Científica
Publicado em /02/2007 Português
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Cognitive psychology has provided clinicians with specific tools for analyzing the processes of cognition (memory, language) and executive functions (attention-concentration, abstract reasoning, planning). Neuropsychology, coupled with the neurosciences (including neuroimaging techniques), has authenticated the existence of early disorders affecting the “superior or intellectual” functions of the human brain. The prevalence of cognitive and attention disorders is high in adults because all the diseases implicating the central nervous system are associated with cognitive correlates of variable intensity depending on the disease process and the age of the patient. In some pathologies, cognitive impairment can be a leading symptom such as in schizophrenia, posttraumatic stress disorder or an emblematic stigmata as in dementia including Alzheimer’s disease. Paradoxically, public health authorities have only recognized as medications for improving cognitive symptoms those with proven efficacy in the symptomatic treatment of patients with Alzheimer’s disease; the other cognitive impairments are relegated to the orphanage of syndromes and symptoms dispossessed of medication. The purpose of this review is to promote a true “pharmacology of cognition” based on the recent knowledge in neurosciences. Data from adult human beings...

Interaction Between Nicotinic and Dopaminergic Therapies on Cognition in a Chronic Parkinson Model

Decamp, E.; Schneider, J. S.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Português
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26.54%
While levodopa therapy for PD may effectively relieve motor symptoms, many of the cognitive deficits experienced by PD patients (and in animal models of PD) are not effectively managed by this treatment. In contrast, previous work has shown positive effects of nicotinic therapies on cognition in PD models. The present study evaluated the effects of levodopa, nicotine and the nicotinic acetylcholine receptor agonist SIB-1553A alone and in combination on cognition in a non-human primate model of early PD. Three adult male Rhesus monkeys, previously administered low doses of the neurotoxin MPTP over several months to produce cognitive deficits, were trained to perform a modified spatial delayed response task in which the attentional demands of the task were manipulated by varying the duration of the cue presentation while keeping the memory demands of the task low and constant. Task performance was assessed after administration of levodopa, nicotine ditartrate, or SIB-1553A and after administration of drug combinations. Animals performed normally when task attentional load was low (i.e., with long cue durations) but performance was significantly impaired on short cue duration trials. Levodopa further impaired performance on short cue duration trials and induced a deficit on long cue duration trials. Nicotine and SIB-1553A improved performance on short cue trials and when co-administered with levodopa...

nAChR agonist-induced cognition enhancement: integration of cognitive and neuronal mechanisms

Sarter, Martin; Parikh, Vinay; Howe, William M.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Português
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26.54%
The identification and characterization of drugs for the treatment of cognitive disorders has been hampered by the absence of comprehensive hypotheses. Such hypotheses consist of (a) a precisely defined cognitive operation that fundamentally underlies a range of cognitive abilities and capacities and, if impaired, contributes to the manifestation of diverse cognitive symptoms; (b) defined neuronal mechanisms proposed to mediate the cognitive operation of interest; (c) evidence indicating that the putative cognition enhancer facilitates these neuronal mechanisms; (d) and evidence indicating that the cognition enhancer facilitates cognitive performance by modulating these underlying neuronal mechanisms. The evidence on the neuronal and attentional effects of nAChR agonists, specifically agonists selective for α4β2* nAChRs, has begun to support such a hypothesis. nAChR agonists facilitate the detection of signals by augmenting the transient increases in prefrontal cholinergic activity that are necessary for a signal to gain control over behavior in attentional contexts. The prefrontal microcircuitry mediating these effects include α4β2* nAChRs situated on the terminals of thalamic inputs and the glutamatergic stimulation of cholinergic terminals via ionotropic glutamate receptors. Collectively...

Perceived Social Isolation and Cognition

Cacioppo, John T.; Hawkley, Louise C.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Português
Relevância na Pesquisa
26.54%
Social species, from Drosophila melanogaster to Homo sapiens, fare poorly when isolated. Homo sapiens, an irrepressibly meaning-making species, are, in normal circumstances, dramatically affected by perceived social isolation. Research indicates that perceived social isolation (i.e., loneliness) is a risk factor for, and may contribute to, poorer overall cognitive performance, faster cognitive decline, poorer executive functioning, more negativity and depressive cognition, heightened sensitivity to social threats, a confirmatory bias in social cognition that is self-protective and paradoxically self-defeating, heightened anthropomorphism, and contagion that threatens social cohesion. These differences in attention and cognition impact emotions, decisions, behaviors, and interpersonal interactions that may contribute to the association between loneliness and cognitive decline and between loneliness and morbidity more generally.

BMP Signaling Mediates Effects of Exercise on Hippocampal Neurogenesis and Cognition in Mice

Gobeske, Kevin T.; Das, Sunit; Bonaguidi, Michael A.; Weiss, Craig; Radulovic, Jelena; Disterhoft, John F.; Kessler, John A.
Fonte: Public Library of Science Publicador: Public Library of Science
Tipo: Artigo de Revista Científica
Publicado em 20/10/2009 Português
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26.54%
Exposure to exercise or to environmental enrichment increases the generation of new neurons in the adult hippocampus and promotes certain kinds of learning and memory. While the precise role of neurogenesis in cognition has been debated intensely, comparatively few studies have addressed the mechanisms linking environmental exposures to cellular and behavioral outcomes. Here we show that bone morphogenetic protein (BMP) signaling mediates the effects of exercise on neurogenesis and cognition in the adult hippocampus. Elective exercise reduces levels of hippocampal BMP signaling before and during its promotion of neurogenesis and learning. Transgenic mice with decreased BMP signaling or wild type mice infused with a BMP inhibitor both exhibit remarkable gains in hippocampal cognitive performance and neurogenesis, mirroring the effects of exercise. Conversely, transgenic mice with increased BMP signaling have diminished hippocampal neurogenesis and impaired cognition. Exercise exposure does not rescue these deficits, suggesting that reduced BMP signaling is required for environmental effects on neurogenesis and learning. Together, these observations show that BMP signaling is a fundamental mechanism linking environmental exposure with changes in cognitive function and cellular properties in the hippocampus.

Physical Activity Levels and Cognition in Women With Type 2 Diabetes

Devore, Elizabeth E.; Kang, Jae Hee; Okereke, Olivia; Grodstein, Francine
Fonte: Oxford University Press Publicador: Oxford University Press
Tipo: Artigo de Revista Científica
Português
Relevância na Pesquisa
26.54%
Persons with type 2 diabetes have a high risk of late-life cognitive impairment, and physical activity might be a potential target for modifying this risk. Therefore, the authors evaluated the association between physical activity level and cognition in women with type 2 diabetes. Beginning in 1995–2000, cognitive function was assessed in 1,550 Nurses’ Health Study participants aged ≥70 years with type 2 diabetes. Follow-up assessments were completed twice thereafter, at 2-year intervals. Multivariate-adjusted linear regression models were used to obtain mean differences in baseline cognitive scores and cognitive decline across tertiles of long-term physical activity. Initial results from age- and education-adjusted models indicated that greater physical activity levels were associated with better baseline cognition (for a global score averaging scores from 6 cognitive tests, P-trend = 0.02). However, results were substantially attenuated after adjustment for multiple potential confounders, largely because of physical disability indicators (global score: P-trend = 0.06); for example, the mean difference for the global score was 0.07 standard units (95% confidence interval: −0.01, 0.15) when comparing extreme tertiles. Results were similar for cognitive decline. These findings indicate little overall association between physical activity and cognition after adjustment for disability factors in older women with type 2 diabetes.

Cognition and incident coronary heart disease in late midlife: The Whitehall II study

Singh-Manoux, Archana; Sabia, Séverine; Kivimaki, Mika; Shipley, Martin J.; Ferrie, Jane E.; Marmot, Michael G.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em 01/11/2009 Português
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The purpose of this study was to investigate whether cognitive function in midlife predicts incident coronary heart disease (CHD), followed up over 6 years. Data on 5292 (28% women, mean age 55) individuals free from CHD at baseline were drawn from the British Whitehall II study. We used Cox regression to model the association between cognition and CHD in analyses adjusted for socio-demographic variables, cardiovascular risk factors and health behaviors. The results show a one standard deviation lower score on the “general” cognitive measure and measures of reasoning and vocabulary to be associated with elevated CHD risk. There was some evidence that these effects differed between high and low socioeconomic status (SES) groups with associations only seen in the low SES group. These results were not explained by threshold effects or by the different SES groups representing different parts of the cognitive test score distribution. Three other possible explanations of these results are discussed: sub clinical vascular disease drives the observed association but no effect is observed in the high SES group due to compensation provided by greater cognitive reserve, cognition is a marker of overall bodily integrity particularly in low-SES groups...

Natural Language Query in the Biochemistry and Molecular Biology Domains Based on Cognition Search™

Elizabeth J. Goldsmith; Saurabh Mendiratta; Radha Akella; Kathleen Dahlgren
Fonte: Nature Preceedings Publicador: Nature Preceedings
Tipo: Manuscript
Português
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Motivation: With the tremendous growth in scientific literature, it is necessary to improve upon the standard pattern matching style of the available search engines. Semantic NLP may be the solution to this problem. Cognition Search (CSIR) is a natural language technology. It is best used by asking a simple question that might be answered in textual data being queried, such as MEDLINE. CSIR has a large English dictionary and semantic database. Cognition’s semantic map enables the search process to be based on meaning rather than statistical word pattern matching and, therefore, returns more complete and relevant results. The Cognition Search engine uses downward reasoning and synonymy which also improves recall. It improves precision through phrase parsing and word sense disambiguation. Result: Here we have carried out several projects to "teach" the CSIR lexicon medical, biochemical and molecular biological language and acronyms from curated web-based free sources. Vocabulary from the Alliance for Cell Signaling (AfCS), the Human Genome Nomenclature Consortium (HGNC), the United Medical Language System (UMLS) Meta-thesaurus, and The International Union of Pure and Applied Chemistry (IUPAC) was introduced into the CSIR dictionary and curated. The resulting system was used to interpret MEDLINE abstracts. Meaning-based search of MEDLINE abstracts yields high precision (estimated at >90%)...

“A princesa que tudo via”: cognitive and creative processes in the literacy doi:10.5007/1807-1384.2010v7n2p192; “A princesa que tudo via”: procesos cognitivos y creativos en la alfabetización doi:10.5007/1807-1384.2010v7n2p192; “A princesa que tudo via”: processos cognitivos e criativos na alfabetização

Neves, Gisélia Oliveira de Sá; Universidade Braz Cubas; Voss, Rita de Cássia Ribeiro; Universidade Braz Cubas
Fonte: Universidade Federal de Santa Catarina Publicador: Universidade Federal de Santa Catarina
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; Pesquisa bibliográfica ; experiências em sala de aula; ; Formato: application/pdf
Publicado em 22/07/2010 Português
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The article reflects theoretical foundations on the cognitive processes in literacy. 'A princesa que tudo via' is a metaphor, a tool that facilitates the understanding of the human cognition and the acquisition of literacy. It is a procedure that allows us to consider the narrative elements of the text in analogy to recent studies on human cognition and creativity. Such narratives configure themselves in guiding principles for the creation of strategies for literacy, in triggering and operating, within the same tune, the bio-cultural dimensions of human cognition. The principle of recursion allows thinking of both the autonomy and creativity of the subject activated by the culture, by its symbolic, imaginary and cultural dimensions, which pervade the experience of the human being, triggering in him, the subjective states that make the cognition possible. In a complex perspective, the principles abstracted from the tale allow to see the eco-self-dependent feature of the constitution of the subject of knowledge. The creativity emerges from the dynamic dependence-autonomy implicit in learning that must be considered by the teacher in the strategies for literacy teaching.  ; El artículo se ocupa de las reflexiones teóricas sobre el proceso cognitivo de la alfabetización. El cuento "A princesa que tudo via"  es una metáfora utilizada para facilitar la comprensión sobre el tema investigado. Se trata de un procedimiento que permite examinar los elementos narrativos del texto en analogía con los recientes estudios sobre la cognición y la creatividad humanas. Estos relatos se configuran en los principios rectores para la construcción de estrategias para la alfabetización...