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alpha(1)-Adrenoceptors in the lateral septal area modulate food intake behaviour in rats

SCOPINHO, A. A.; RESSTEL, L. B. M.; CORREA, F. M. A.
Fonte: WILEY-BLACKWELL Publicador: WILEY-BLACKWELL
Tipo: Artigo de Revista Científica
Português
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Background and purpose: Control of food intake is a complex behaviour which involves many interconnected brain structures. The present work assessed if the noradrenergic system in the lateral septum (LS) was involved in the feeding behaviour of rats. Experimental approach: In the first protocol, the food intake of rats was measured. Then non-food-deprived animals received either 100 nL of 21 nmol of noradrenaline or vehicle unilaterally in the LS 10 min after local 10 nmol of WB4101, an alpha(1)-adrenoceptor antagonist, or vehicle. In the second protocol, different doses of WB4101 (1, 10 or 20 nmol in 100 nL) were microinjected bilaterally into the LS of rats, deprived of food for 18 h and food intake was compared to that of satiated animals. Key results: One-sided microinjection of noradrenaline into the LS of normal-fed rats evoked food intake, compared with vehicle-injected control animals, which was significantly reduced by alpha(1)-adrenoceptor antagonism. In a further investigation, food intake was significantly higher in food-deprived animals, compared to satiated controls. Pretreatment of the LS with WB4101 reduced food intake in only food-deprived animals in a dose-related manner, suggesting that the LS noradrenergic system was involved in the control of food intake. Conclusion and implications: Activation by local microinjection of noradrenaline of alpha(1)-adrenoceptors in the LS evoked food intake behaviour in rats. In addition...

Refeições em família e sua relação com consumo alimentar e estado nutricional de adolescentes; Family meals and its relation to food intake and adolescents nutritional status

Araki, Erica Lie
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 07/10/2010 Português
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Introdução: Os adolescentes são considerados vulneráveis do ponto de vista nutricional, pois tendem a omitir refeições e não realizá-las com a família. Refeições em família propiciam oportunidade de socializar o adolescente e ensiná-lo sobre nutrição e bons hábitos alimentares. Objetivos Verificar associação entre freqüência de refeições em família com o consumo de alimentos e estado nutricional de adolescentes. Metodologia: Foram estudados adolescentes do ensino médio de 12 escolas técnicas da região metropolitana de São Paulo, com amostragem aleatória simples. Os adolescentes responderam dois questionários, sendo um sobre atitude alimentar e outro sobre a freqüência alimentar. Foi realizada mensuração antropométrica e calculado o Índice de Massa Corporal (IMC) para analisar o estado nutricional, utilizando-se o IMC/ idade. Para a análise dos dados foram utilizados os testes Qui-quadrado e a Análise de Variância e também comparações múltiplas quando houve diferenças significativas entre médias. Resultados: Foram avaliados 1167 adolescentes, sendo 51por centomeninos e 49por centomeninas. A média de IMC para ambos os gêneros foi de 22,28kg/m2 (±3,9) e observou-se baixa ingestão de verduras...

Desenvolvimento e avaliação da usuabilidade de um recordatório de 24 horas estruturado e computadorizado para acompanhamento do consumo alimentar de escolares; Developing and evaluation of the usability of a structured and automated 24-Hour Recall to evaluate school children food intake

Ferri, Bruna Furer
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 09/12/2011 Português
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Introdução: A avaliação do consumo alimentar de crianças e adolescentes representa um desafio na pesquisa epidemiológica. O Recordatório de 24 horas (R24h) é considerado um ótimo método para coletar dados dietéticos e é muito utilizado no acompanhamento alimentar da população. Porém requer entrevistadores altamente treinados, o que dificulta o uso em pesquisas de grandes amostras. Objetivo. Desenvolver um Recordatório de 24 horas estruturado e computadorizado (R24ec) para a avaliação do consumo alimentar de escolares e testar a usabilidade deste sistema. Métodos. Os alimentos escolhidos para o R24ec foram pré-definidos a partir de um banco de dados secundário. O R24ec inclui seis refeições prédefinidas, embutidas em questões que contextualizam as rotinas e locais do dia anterior. Contém ainda uma lista de alimentos dividida em grupos alimentares e subgrupos. Durante a entrevista, itens não listados podem ser adicionados em espaço previsto para este uso. A base de dados de composição de alimentos é composta pela tabela TACO. O R24ec ainda inclui um atlas fotográfico, contendo diferentes tipos de alimentos que serve como auxílio visual para que os entrevistados possam selecionar os tamanhos de porções. Realizou-se um teste com o R24ec em uma escola pública de Guarulhos com 73 escolares. A usabilidade foi testada por 17 profissionais da área da tecnologia da informação através de um questionário que avalia a usabilidade de sistemas utilizando a lógica Fuzzy baseado na ISO. Resultados. Foi desenvolvido um instrumento computadorizado contendo uma lista de aproximadamente 120 alimentos com média de três tamanhos de porções. Dos escolares pesquisados...

Ingestão habitual de alimentos entre indivíduos do Município de São Paulo - estudo de base populacional; Habitual food intake among individual from São Pulo - Brazil a population-based survey

Verly Junior, Eliseu
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 11/01/2012 Português
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Introdução: A estimativa da ingestão habitual de alimentos requer o uso de técnicas estatísticas apropriadas. Para alguns alimentos, é possível observar consumo igual a zero em um ou vários dias de coleta, mesmo em indivíduos que os consomem periodicamente. Assim, os métodos devem ser capazes de tratar duas questões: 1) a distribuição com zero inflacionado; e 2) a correlação existente entre a probabilidade de consumir um alimento e a quantidade (tamanho da porção) consumida do mesmo. Objetivo: Investigar aspectos metodológicos do um método para estimar o consumo habitual de alimentos, bem como sua aplicação em estudo na população. Métodos: Inicialmente, utilizando amostra do National Health and Nutrition Examination Survey 2007-2008, foram estimadas distribuição do consumo habitual de vegetais verdes escuros a partir de amostras de diferentes tamanhos e diferentes percentuais de indivíduos com dois recordatórios de 24 horas (R24h). Posteriormente, foram utilizados dados do Inquérito de Saúde de São Paulo, estudo transversal, de base populacional, (n=716), cujos participantes responderam dois R24 horas e um questionário de freqüência alimentar (QFA). Verificou-se o efeito da inclusão do QFA como co-variável na melhora da predição do modelo do consumo de alimentos. Por fim...

Food intake of Macrobrachium rosenbergii during larval development

de Barros, H. P.; Valenti, Wagner Cotroni
Fonte: Elsevier B.V. Publicador: Elsevier B.V.
Tipo: Artigo de Revista Científica Formato: 165-176
Português
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This work investigates the acceptance of different food types and sizes by Macrobrachium rosenbergii during each larval stage. Food intake of dry and wet formulated diets of four different size classes (250-425, 425-710, 710-1000 and 1000-1190 mum), as well as Artemia nauplii, was determined. Larvae of each zoeal stage were stocked in beakers and fed ad libitum. After 30-45 min, the digestive tract of each larva was observed under a stereomicroscope. Acceptance was evaluated by food intake frequency (FFI). There was no significant interaction (P<0.05) between inert diet size and FFI for each larval stage. Therefore, food intake during larval development is independent of food particle size. The ingestion of Artemia nauplii, was significantly higher by larvae between stages II and VI. Between stages VII and XI, FFI for Artemia nauplii and wet diet was similar, while the FFI of the dry diet was similar to live food between stages IX and XI. The wet diet was ingested by more than 50% of the larvae only from stage VII onwards, while the dry diet from stage VIII onwards. These results indicate that larvae could be fed Artemia nauplii only until stage VI. Diet supplementation should start from stage VII onwards, using food particles varying from 250 to 1190 mum. (C) 2003 Elsevier B.V. B.V. All rights reserved.

Food intake in women two years or more after bariatric surgery meets adequate intake requirements

Sousa Novais, Patricia Fatima; Rasera, Irineu; de Souza Leite, Celso Vieira; Marin, Flavia Andreia; Marques de Oliveira, Maria Rita
Fonte: Pergamon-Elsevier B.V. Ltd Publicador: Pergamon-Elsevier B.V. Ltd
Tipo: Artigo de Revista Científica Formato: 335-341
Português
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Restricted food intake after bariatric surgery can be an important factor both in the long-term control of body weight and in the onset of nutritional deficiencies. The objective of this study was to assess the adequacy of food intake in women two or more years after bariatric surgery according to the excess weight lost. A group of 141 women who underwent banded Roux-en-Y gastric bypass (RYGB) was divided according to the percentage of excess weight they lost (%EWL)<50; 50-175; = 75. The habitual energy and nutrient intakes were determined by a 24-hour recall over two days and the probability of adequate intake was based on the Dietary Reference Intake. The mean total estimated energy requirement (EER) as well as energy, macronutrient and cholesterol intakes did not differ among the groups. Only the %EWL < 50 group had an intake equal to their EER, but they presented a higher number of inadequacies, such as low levels of magnesium, folic acid and vitamins C and E. Calcium and dietary fiber intakes were extremely low in all three groups. In conclusion, weight loss after surgery is associated with food habits that favor energy intake over micronutrient intake. (C) 2012 Elsevier B.V. All rights reserved.

2-DEOXYGLUCOSE-INDUCED FOOD-INTAKE BY NILE TILAPIA, OREOCHROMIS-NILOTICUS (L)

Delicio, H. C.; Vicentinipaulino, MLM
Fonte: Associação Brasileira de Divulgação Científica (ABRADIC) Publicador: Associação Brasileira de Divulgação Científica (ABRADIC)
Tipo: Artigo de Revista Científica Formato: 327-331
Português
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The alimentary and glycemic responses to cytoglycopenia were studied in thirty-one Nile tilapia alevins of indeterminate sex and age, measuring on average 10.67 +/- 0.82 cm. The cytoglycopenia was provoked by ip injection of 60 mg/kg 2-deoxy-D-glucose (2-DG, N = 16). The control group (N = 15) was submitted to ip injection of 0.2 ml saline. Blood samples for glucose determination were obtained before and three hours after drug administration by cardiac puncture. Food was then offered ad libitum. One hour later the animals were sacrificed and their stomachs removed. The difference in wet weight between full and empty stomach was utilized to quantify the food intake. Median food intake was 0.3877 g for the fish treated with 2-DG and 0.107 g for the animals injected with saline. This difference was statistically significant by the Mann-Whitney test (P<0.05). The median values of blood glucose levels before drug injection were 46.19 mg/100 ml in the 2-DG-treated fish and 44.54 mg/100 ml in the control group. Three hours after drug administration, the values were 48.64 mg/100 ml in the experimental group and 56.90 mg/100 ml in the control group. The difference between the values of blood glucose before and after the drug was not significant for either group. We conclude that glucoprivation provokes food intake in fish and that the same glucoprivation was not sufficient to provoke hyperglycemia.

Commissural nucleus of the solitary tract lesions reduce food intake and body weight gain in rats

Menani, Jose Vanderlei; Colombari, Eduardo; Talman, William T.; Johnson, Alan Kim
Fonte: Universidade Estadual Paulista Publicador: Universidade Estadual Paulista
Tipo: Artigo de Revista Científica Formato: 102-108
Português
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This study investigated the effects of an electrolytic lesion of the commissural subnucleus of the nucleus of the solitary tract (commNTS) on bodyweight, daily food and water intake, and plasma glucose and insulin in rats. In the first 6 days following brain surgery, commNTS lesioned rats reduced daily food intake by 80% compared to rats with sham lesions. After this period rats with lesions of commNTS started recovering food intake, but intake remained significantly reduced until the 12th day after surgery. A reduction in body weight was observed 4 days after surgery and reached a maximum on the 12th day. After this, a partial recovery of body weight was observed, but weight remained significantly reduced compared to weights of rats with sham lesions through the conclusion of the study. Food intake and body weight gain in other rats with partial lesions of the commNTS or with lesions outside the commNTS did not differ from rats with sham lesions with regard to those variables. Daily water intake and plasma glucose and insulin were not changed by the commNTS lesions. These results suggest that commNTS is involved with mechanisms that control food intake and body weight in rats.

Food intake and nutritional status of hospitalised older people

De Oliveira, Maria Rita Marques; Leandro-Merhi, Vânia Aparecida
Fonte: Universidade Estadual Paulista Publicador: Universidade Estadual Paulista
Tipo: Artigo de Revista Científica Formato: 196-200
Português
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Background and aims. Disease is influenced by the nutritional status of the individual. We have assessed the relationship between nutritional status and food intake among recently hospitalised older people. Methods. A cross-sectional study was undertaken with 240 older people in a hospital that provides care for the public and private healthcare systems. Nutritional status was classified by the MNA (Mini Nutritional Assessment) into: malnourished, risk of malnutrition and without malnutrition. Food intake was estimated by the reported food intake during a typical day. The Kruskal-Wallis test was used to compare the medians and the correlation coefficient of Spearman to verify the relationship between the consumption of energy, protein and vitamin C and MNA scores. Results. 33.8% were classified as adequate regarding nutritional status; 37.1% were classified as being at risk of malnutrition and 29.1% were classified as malnourished. The malnourished individuals reported significantly less energy and nutrient intake than those at risk of malnutrition or those without malnutrition (P=0.001). Not all nutrient intake, just some (iron, cholesterol and fibre), were lower in malnourished people. Conclusions and implications for practice. Deterioration of the nutritional status of older people is accompanied by a reduction in energy and some nutrient intake. The investigation of food intake in older people could provide important information about nutritional risk. © 2010 Blackwell Publishing Ltd.

Insulin action/signaling in amygdala of controls and obeses animals : effects on food intake, inflammation and ER stress = Regulação da ação e sinalização de insulina em amígdala de animais controles e obesos : efeitos na ingestão alimentar, via inflamatória e stress de retículo endoplasmático; Regulação da ação e sinalização de insulina em amígdala de animais controles e obesos : efeitos na ingestão alimentar, via inflamatória e stress de retículo endoplasmático

Maria Fernanda Condes Areias
Fonte: Biblioteca Digital da Unicamp Publicador: Biblioteca Digital da Unicamp
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 14/12/2012 Português
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A insulina tem efeitos anorexigênicos, reduzindo o peso corporal. Entretanto, a maior parte dos estudos teve como foco a ação e sinalização de insulina no hipotálamo. Assim, o primeiro objetivo do trabalho foi investigar a expressão e grau de fosforilação das proteínas da via de sinalização de insulina (IR/Akt), assim como a modulação da ingestão alimentar após estímulo com insulina na região da amígdala em animais controles. No segundo objetivo, investigamos se o bloqueio farmacológico da via da insulina com LY24002 na amígdala alterou a ingestão alimentar em resposta à insulina. O consumo de dieta hiperlipídica tem sido associado à resistência à insulina no hipotálamo. Assim, o terceiro objetivo foi investigar se a obesidade induz resistência à insulina nessa região e em adição investigar se a via inflamatória IKK/NFkB e o ER stress estavam alterados em amígdala de animais obesos. Obervou-se que após a injeção de insulina na amígdala, não houve diferença no peso corpóreo após 24 horas em animais controles. Em relação à ingestão alimentar, quatro horas após a injeção de insulina na amígdala, não houve diferença, entretanto, após 8, 12 e 24 horas houve uma diminuição na ingestão alimentar em animais controles. Após o bloqueio da PI3q com o inibidor farmacológico LY (240002)...

Involvement of β3-adrenergic receptors in the control of food intake in rats

Kanzler,S.A.; Januario,A.C.; Paschoalini,M.A.
Fonte: Associação Brasileira de Divulgação Científica Publicador: Associação Brasileira de Divulgação Científica
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/11/2011 Português
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This study examined the food intake changes evoked by intracerebroventricular (icv) injection of a selective agonist (BRL37344, 2 and 20 nmol) or antagonist (SR59230A, 10 and 50 nmol) of β3-adrenergic receptors in 24-h fasted rats (adult male Wistar rats, 200-350 g, N = 6/treatment). The animals were also pretreated with saline icv (SAL) or SR59230A (50 nmol) followed by BRL37344 (20 nmol) or SAL in order to determine the selectivity of the effects evoked by BRL37344 on food intake or the selectivity of the effects evoked by SR59230A on risk assessment (RA) behavior. The highest dose of BRL37344 (N = 7) decreased food intake 1 h after the treatment (6.4 ± 0.5 g in SAL-treated vs 4.2 ± 0.8 g in drug-treated rats). While both doses of SR59230A failed to affect food intake (5.1 ± 1.1 g for 10 nmol and 6.0 ± 1.8 g for 50 nmol), this treatment reduced the RA frequency (number/30 min) (4 ± 2 for SAL-treated vs 1 ± 1 for 10 nmol and 0.5 ± 1 for 50 nmol SR59230A-treated rats), an ethological parameter related to anxiety. While pretreatment with SR59230A (7.0 ± 0.5 g) abolished the hypophagia induced by BRL37344 (3.6 ± 0.9 g), BRL37344 suppressed the reduction in RA frequency caused by SR59230A. These results show that the hypophagia caused by BRL37344 is selectively mediated by β3-adrenergic receptors within the central nervous system. Moreover...

The doubly-labeled water method and food intake surveys: a confrontation

BELLISLE,France
Fonte: Pontifícia Universidade Católica de Campinas Publicador: Pontifícia Universidade Católica de Campinas
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/08/2001 Português
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Surveys of food intake in humans, following measurements of energy expenditures in free-living persons, obtained by the doubly-labeled water technique, have been severely questioned in recent years. The present article reviews studies performed in both adults and children, comparing energy intake and expenditures in the same individuals. In adults, reported intake is often insufficient to cover minimal energy needs. The typical level of "under-reporting" is about 20%, and it is even higher in obese subjects. Intake data obtained from children are more valid than data from adults. Different survey methods yield differing degrees of agreement between intake and expenditure measurements using the doubly labeled water technique: frequency questionnaires tend to induce over-reporting, whereas the classical 24 hours recall is very susceptible to large under-reporting. Even obese adults can provide accurate reports of their daily food intake if properly trained and motivated. The interpretation of data obtained with the doubly labeled water method should integrate the considerable day-to-day variations observed in human food intake.

Effect of glycomacropeptide fractions on cholecystokinin and food intake

Keogh, J.; Woonton, B.; Taylor, C.; Janakievski, F.; Desilva, K.; Clifton, P.
Fonte: C A B I Publishing Publicador: C A B I Publishing
Tipo: Artigo de Revista Científica
Publicado em //2010 Português
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Glycomacropeptide (GMP) is the hydrophilic 64-amino acid C-terminal glycopeptide released into cheese whey when kappa-casein is cleaved by chymosin. GMP exists as a mixture of different glycoforms due to the carbohydrates sialic acid (N-acetylneuraminic acid, NeuNAc), galactose (Gal), galactosamine and glucosamine attached by O-glycosidic linkages. GMP reportedly stimulates the release of cholecystokinin (CCK), which may promote satiety. The objectives of the present study were to manufacture three glycoforms of GMP, minimally glycosylated GMP (3.5 (sd 0.1) % NeuNAc and 1.5 (sd 0.1) % Gal), glycosylated GMP (12.0 (sd 0.3) % NeuNAc and 4.2 (sd 0.2) % Gal) and a GMP-depleted whey protein concentrate, and to assess the effects of these fractions relative to glucose on CCK, subjective measures of satiety and food intake. In a randomised double-blind acute study, twenty overweight/obese males (56.9 (sd 7.2) years, 97.4 (sd 8.1) kg, 31.5 (sd 3.0) kg/m2) were recruited to consume four 50 g preloads (two GMP preparations, GMP-depleted whey and glucose) containing 895 kJ. Blood samples and subjective measures of satiety were collected before and at 15, 30, 60, 90, 120 and 180 min after the consumption of preload, and CCK levels were measured. A lunchtime meal of hot food was provided from which subjects ate ad libitum until satisfied. Energy and nutrient intakes from the food consumed were calculated. There was no significant difference in CCK levels...

The fetal origins of obesity: early origins of altered food intake

Muhlhausler, B.; Ong, Z.
Fonte: Bentham Science Publishers Ltd Publicador: Bentham Science Publishers Ltd
Tipo: Artigo de Revista Científica
Publicado em //2011 Português
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There is now clear evidence from population-based and experimental animal studies that maternal obesity and maternal overnutrition, particularly excessive intake of high-fat and high-sugar diets, is associated with an increased risk of obesity and type 2 diabetes in the offspring. Whilst the physiological reasons for this association are still not fully understood, one of the key pathways appears to be the ability of exposure to an oversupply of energy, fat and sugar during critical windows of development to program an increased food intake in the offspring. This review will focus on our current understanding of the programming of food intake, with a focus on the importance of the maternal diet. Specifically, we will discuss how exposure to an increased energy supply before birth and in early infancy, and/or increased maternal intake of palatable foods alters the development of the systems regulating appetite and food preferences, and how these changes interact to promote excess consumption and thus predispose the offspring to weight gain and obesity.; http://www.ncbi.nlm.nih.gov/pubmed/21831032; B.S. Muhlhausler and Z.Y. Ong

Einfluss von Metergoline auf die Nahrungsaufnahme und das Körpergewicht nach Gastrektomie bei der Ratte. Dosis-Wirkungsbeziehung und Langzeiteffekte; Influence of Metergoline on food intake and body weight after total gastrectomy of the rat. Dose-dependant effects and long-term results

Kless, Steffen
Fonte: Universidade de Tubinga Publicador: Universidade de Tubinga
Tipo: Dissertação
Português
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Durch die Aktivierung verschiedener Serotoninrezeptorsubtypen hemmt Serotonin die Nahrungsaufnahme. Dieser hypophage Effekt konnte sowohl nach zentraler als auch nach peripherer Stimulation von Serotoninrezeptoren beobachtet werden. Nach Gastrektomie ist der Serotoninspiegel in der Portalvene deutlich erhöht. Somit könnte Serotonin zumindest partiell für den postoperativ auftretenden Gewichtsverlust nach Gastrektomie verantwortlich sein. Material und Methoden: In unserer Studie injizierten wir gastrektomierten Ratten intraperitoneal verschiedene Konzentrationen des 5-HT1/2-Rezeptor- antagonisten Metergoline. In einer zweiten Versuchsreihe implantierten wir gastrektomierten Ratten intraperitoneal osmotische Pumpen, die Metergoline oder Lösungsmittel über einen Zeitraum von zwölf Wochen kontinuierlich abgaben. Hierdurch sollte untersucht werden, ob die kontinuierliche Gabe von Metergoline die Nahrungsaufnahme auch langfristig beeinflusste und dadurch eventuell ein Anstieg des Körpergewichts zu verzeichnen war. Ergebnisse: Metergoline erhöhte die Nahrungsaufnahme signifikant. Die deutlichste Steigerung der Nahrungsaufnahme ließ sich mit der Dosierung 1,0mg/kg Körpergewicht erreichen. So konnte die Nahrungsaufnahme hiermit innerhalb der ersten Stunde post injectionem um 207% gegenüber den mit Lösungsmittel behandelten Tieren gesteigert werden (p=0...

Die Wirkung von frühzeitiger Nahrungsaufnahme auf die Dickdarmmotilität nach kolo-rektalen Eingriffen. Kombinierte Manometrie-Barostat-Messungen bei Patienten; The Effect of Early Oral Food Intake on Colonic Motility after Colo-Rektal Surgery. Combined Manometrie-barostat-Recordings at Patients

Thiers, Guido
Fonte: Universität Tübingen Publicador: Universität Tübingen
Tipo: Dissertation; info:eu-repo/semantics/doctoralThesis
Português
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Hintergrund: Nach Operationen tritt regelmäßig eine von Art und Größe des Eingriffs abhängige Darmfunktionsstörung auf. Dieser Zustand wird als postoperativer Ileus bezeichnet. Der postoperative Verlauf, d. h. das Befinden der Patienten, Dauer des Krankenhausaufenthaltes und Behandlungskosten, sind von der Erholung der gastro-intestinalen Motilität abhängig. Therapeutisch stehen Nahrungskarenz, parenterale Ernährung, und die Gabe von Abführmitteln und Parasympatikomimetika im Vordergrund. Nahrungsaufnahme bewirkt bei Gesunden über den gastro-kolischen Reflex (gastro-colic-response) eine Anregung der Dickdarmmotorik. Das Ziel dieser Studie war es, die Wirkung einer frühpostoperativen Nahrungsaufnahme auf die postoperative Kolonmotilität zu untersuchen. Methodik: Bei 15 Patienten, die mit einer Kolonteilresektion behandelt wurden, wurde intraoperativ ein kombinierter Manometrie-Barostat-Messkatheter ins Kolon eingelegt. Am 1.-3. Tag postoperativ wurde den Patienten ein hochkalorisches Testgetränk mit definierter Zusammensetzung verabreicht. Die Kolonmotorik wurde mit einem kombinierten Manometrie-Barostat- Meßsystem vor, während und nach der Nahrungsaufnahme gemessen. Die Meßapparaturen und deren Einstellung und Datenspeicherung erfolgte standardisiert. Es wurden der Motilitätsindex (Fläche unter der Kurve pro Minute)...

Relation between food intake and visual analogue scale ratings of appetite and other sensations in healthy older and young subjects

Parker, B.; Sturm, K.; MacIntosh, C.; Feinle-Bisset, C.; Horowitz, M.; Chapman, I.
Fonte: Nature Publishing Group Publicador: Nature Publishing Group
Tipo: Artigo de Revista Científica
Publicado em //2004 Português
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OBJECTIVE: Visual analogue scales are widely used in appetite research, yet the validity of these scales to evaluate appetite and mood has not been assessed in older subjects. The aim of this study was to determine the relations between food intake and visual analogue scale (VAS) ratings of appetite and nonappetite sensations in healthy older and young subjects. DESIGN: Retrospective combined analysis of four single-blind, randomised, controlled appetite studies. SETTING: All studies were conducted in the University of Adelaide, Department of Medicine, Adelaide, Australia. SUBJECTS: A total of 45 healthy young men (n=24) and women (n=21) aged 18-35 y and 45 healthy older men (n=24) and women (n=21) aged 65-85 y were recruited by advertisement. INTERVENTIONS: Oral, intraduodenal or intravenous administration of treatments which suppressed food intake were compared to control. Up to 90 min after treatment, a test meal was offered and subjects ate freely for between 30 and 60 min. Perceptions were assessed by 100-mm visual analogue scales administered at regular intervals. RESULTS: Food intake at the test meal was positively related to perceptions of hunger, drowsiness, and calmness at both baseline and premeal (r>0.16, P<0.05), and inversely related to premeal ratings of fullness (r> 0.2...

EVIDENCE FOR INVOLVEMENT OF THE CYSTEINYL LEUKOTRIENE TYPE 2 RECEPTOR (CysLT2R) IN THE REGULATION OF FOOD INTAKE AND BODY WEIGHT AND POSSIBLE ROLE FOR VAGAL AFFERENTS

AL-HELAILI, ALAA
Fonte: Quens University Publicador: Quens University
Tipo: Tese de Doutorado
Português
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67.80974%
The field of food intake and satiety has received increasing interest from the research community in recent years. The mechanisms and factors that regulate satiety gains their importance from the crucial role they play in food consumption and consequently control of body weight. Leukotrienes are mediators that are released in inflammatory conditions. One of the receptors on which Leukotrienes perform their actions is Cysteinyl Leukotriene Receptor Type 2 (CysLT2Rs). Recently, our colleagues made the observation that CysLT2Rs are expressed in vagal afferent neurons. In addition, CysLT2R-/- mice appeared to be heavier than WT (Moos and Funk, unpublished observations). Based on these findings, I hypothesized that CysLT2Rs play a role in regulating food intake via vagal afferent activity. In-vivo studies were performed to characterize body weight gain and investigate whether weight gain was associated with increased food intake. I found that CysLT2R-/- mice not only have significantly higher body weight, but also eat significantly more than CysLT2R+/+ mice. Using calcium imaging techniques, I demonstrated that LTD4 and LTC4 increased calcium Ca2+ influx in nodose ganglion neuron. Moreover, the level of neuronal activation in the brainstem (NTS area) was measured in both groups of mice using immunohistochemical techniques...

Composição corporal, gasto energético e ingestão alimentar em modelos brasileiras; Body composition, energy expenditure and food intake in brazilian fashion models

Rodrigues, Alexandra Magna; Universidade Federal de São Paulo, Departamento de Pediatria. São Paulo, SP.; Cintra, Isa de Pádua; Universidade Federal de São Paulo, Departamento de Pediatria. São Paulo, SP.; Santos, Luana Caroline dos; Universidade de
Fonte: Universidade Federal de Santa Catarina. Florianópolis, SC. Brasil Publicador: Universidade Federal de Santa Catarina. Florianópolis, SC. Brasil
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; "Avaliado por Pares",; ; Avaliado por Pares; Correlacional Formato: application/pdf; application/pdf
Publicado em 09/12/2008 Português
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67.67969%
http://dx.doi.org/10.5007/1980-0037.2009v11n1p1 O objetivo desse estudo foi comparar a composição corporal, taxa de metabolismo em repouso e ingestão alimentar entre adolescentes modelos e não modelos. Participaram do estudo 33 modelos e 33 não modelos, de 15 a 18 anos, pareadas por idade e IMC. A avaliação da composição corporal foi realizada por meio da técnica de pletismografia. A taxa de metabolismo em repouso (TMR) foi obtida pelo método da calorimetria indireta e a avaliação da ingestão alimentar foi realizada por meio de um registro alimentar de 3 dias alternados. Não houve diferença estatisticamente significante em relação aos valores médios de percentual de gordura corporal entre os grupos estudados (p>0,05). Entretanto, ao classificar as adolescentes quanto ao percentual de gordura corporal, observou-se que nenhuma modelo apresentou percentual de gordura corporal menor do que 15%, enquanto 15,2% das adolescentes não modelos apresentaram baixo percentual de gordura corporal (p<0,05). Os valores de TMR (kcal/d) foram semelhantes entre modelos (1367,22) e não modelos (1309,43) (p>0,05). Em relação à ingestão de energia, observou-se que a média de ingestão energética foi 1480,93kcal ± 582...

Anthropometric, food intake differences and aplicability of low-cost instruments for the measurement of body composition in two distinct groups of individuals with short bowel syndrome

Bizari,Letícia; Silva Santos,Andressa Feijó da; Marchini,Júlio Sérgio; Marques Miguel Suen,Vivian
Fonte: Nutrición Hospitalaria Publicador: Nutrición Hospitalaria
Tipo: info:eu-repo/semantics/article; journal article; info:eu-repo/semantics/publishedVersion Formato: text/html; application/pdf
Publicado em 01/07/2014 Português
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67.70228%
Introduction: Short bowel syndrome is associated with weight loss due to nutrient, electrolyte and fluid malabsorption. In view of the pathophysiology of SBS, all patients would be expected to exhibit similar clinical signs and symptoms, whereas many variations occur probably due to the adaptive capacity of the remaining small intestine in order to compensate for the resected area. Objective: To determine whether there is a difference in nutritional status and food intake between patients receiving PNT, patients who do not receive PNT but are monitored on an ambulatory basis, and control subjects, and 2) to determine body composition by two different methods, i.e., electrical bioimpedance and skin fold measurement. Methods: This was a case-control study where the subjects were divided into three groups: parenteral group (PG) - adults with a history of SBS intermittently using PNT; ambulatory group (AG) - adults with a history of SBS who do not receive PNT; control group (CG) - adults with no history of intestinal resections and/or use of PNT. The volunteers were submitted to measurements of body weight, height, body composition by bioimpedance analysis and assessment of food intake using a food frequency questionnaire. Univariate analysis of variance (ANOVA) with the aid of the SAS® 9.2. software...